TANK ELISA kits are immunoassay tools for the measurement of the protein TRAF family member associated NFKB activator, which is encoded by the TANK gene in humans. Functionally, this protein is known to be an adapter protein involved in I-kappa-B-kinase (IKK) regulation which constitutively binds TBK1 and IKBKE playing a role in antiviral innate immunity. The canonical protein structure is reported to have an amino acid sequence of 425 residues and a mass of 47.8 kDa. It is known to be localized in the cytoplasm and is ubiquitously expressed across many tissue types. As many as 3 protein isoforms have been reported. The protein has been noted to be post-translationally cleaved and phosphorylated. Other alias names for this target include ITRAF, TRAF2, TRAF family member-associated NF-kappa-B activator, and I-TRAF.
Some TANK ELISA kits can detect targets at levels as low as 0.156 ng/mL and as high as 10 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.