TBR1 ELISA kits are immunoassay tools for the measurement of the protein T-box brain transcription factor 1, which is encoded by the TBR1 gene in humans. Functionally, this protein is known to be a transcriptional repressor involved in multiple aspects of cortical development, including neuronal migration, laminar and areal identity, and axonal projection. The canonical protein structure is reported to have an amino acid sequence of 682 residues and a mass of 74.1 kDa. It is known to be localized in the nucleus and is notably expressed in the brain. As many as 2 protein isoforms have been reported. The TBR1 gene has been associated with the disease, Intellectual developmental disorder with autism and speech delay. Other alias names for this target include IDDAS, TES-56, T-box brain protein 1, T-box, brain 1, T-brain-1, and AUTS5.
Some TBR1 ELISA kits can detect targets at levels as low as 0.156 ng/mL and as high as 10 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.