CLN3 ELISA kits are immunoassay tools for the measurement of the protein CLN3 lysosomal/endosomal transmembrane protein, battenin, which is encoded by the CLN3 gene in humans. Functionally, this protein is known to mediate microtubule-dependent, anterograde transport connecting the Golgi network, endosomes, autophagosomes, lysosomes and plasma membrane, and participates in several cellular processes such as regulation of lysosomal pH, lysosome protein degradation, receptor-mediated endocytosis, autophagy, transport of proteins and lipids from the TGN, apoptosis and synaptic transmission. The canonical protein structure is reported to have an amino acid length of 438 residues, a mass of 47.6 kDa, and is a member of the Battenin protein family. It is reported to be expressed in the cortical brain, pancreas, spleen, and testis with weaker expression in the peripheral nerve. As many as 7 protein isoforms have been reported. The protein has been noted to be post-translationally glycosylated and phosphorylated. The CLN3 gene has been associated with the disease, Ceroid lipofuscinosis. Other alias names for this target include BTS, JNCL, battenin, CLN3, battenin, batten disease protein, ceroid-lipofuscinosis, neuronal 3, and BTN1.
Some CLN3 ELISA kits can detect targets at levels as low as 78.125 pg/mL and as high as 20 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.