The following Caspase 4 ELISA kits are useful research tools for the measurement of caspase 4 in biological samples. In humans this protein is encoded by the CASP4 gene. This protein is reported to be an inflammatory caspase that acts as the effector of the non-canonical inflammasome by mediating lipopolysaccharide (LPS)-induced pyroptosis. The canonical protein structure is reported to have an amino acid length of 377 residues, a mass of 43.3 kDa, and is a member of the Peptidase C14A protein family. Its subcellular location is known to be in the membrane, mitochondria, ER, cytoplasm, and is secreted. In addition, it is reported to be widely expressed including in keratinocytes and colonic and small intestinal epithelial cells. As many as 5 protein isoforms have been reported. In certain instances, it is also post-translationally cleaved. This protein may also be known as ICEREL-II, ICH-2, Mih1, Mih1/TX, TX, ICE and Ced-3 homolog 2, ICE(rel)-II, and ICE(rel)II.
There are Caspase 4 ELISA kits that can detect a target at concentrations as low as 39 pg/mL and as high as 100 ng/mL. Use the search filters to narrow your search and click on the ELISA kits below for more detailed information, such as reactivity and assay sensitivity.