KRT18 ELISA kits are immunoassay tools for the measurement of the protein keratin 18, which is encoded by the KRT18 gene in humans. Functionally, this protein is reported to be involved in uptake of thrombin-antithrombin complexes by hepatic cells (By similarity). The canonical protein structure is reported to have an amino acid length of 430 residues, a mass of 48.1 kDa, and is a member of the Intermediate filament protein family. It is known to be localized in the nucleus and cytoplasm and is reported to be expressed in colon, placenta, liver and very weakly in exocervix. The protein has been noted to be post-translationally glycosylated, cleaved and phosphorylated. The KRT18 gene has been associated with the disease, Cirrhosis. Other alias names for this target include CYK18, K18, keratin, type I cytoskeletal 18, cell proliferation-inducing gene 46 protein, cytokeratin 18, and CK-18.
The detection range for different KRT18 ELISA kits can vary, with some assays measuring target concentrations as low as 15.6 pg/mL and as high as 100 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.