FLT4 ELISA kits are immunoassay tools for the measurement of the protein fms related receptor tyrosine kinase 4, which is encoded by the FLT4 gene in humans. Functionally, this protein is reported to be a tyrosine-protein kinase that acts as a cell-surface receptor for VEGFC and VEGFD, and plays an essential role in adult lymphangiogenesis and in the development of the vascular network and the cardiovascular system during embryonic development. The canonical protein structure is reported to have an amino acid length of 1363 residues, a mass of 152.8 kDa, and is a member of the Tyr protein kinase protein family. It is known to be localized in the cell membrane, nucleus, and cytoplasm and is notably expressed in endothelial cells. As many as 3 protein isoforms have been reported. The protein has been noted to be post-translationally phosphorylated and glycosylated. The FLT4 gene has been associated with the disease, Lymphatic malformation. Other alias names for this target include FLT41, LMPH1A, LMPHM1, PCL, VEGFR-3, VEGFR3, vascular endothelial growth factor receptor 3, and CHTD7.
There are FLT4 ELISA kits that can detect a target at concentrations as low as 3 ng/L and as high as 100 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.