The Nesprin 1 ELISA kits listed below utilize specific antibodies for the plate-based assay of Nesprin 1 in various samples. Nesprin 1 is another term for the SYNE1 gene, which encodes the protein, spectrin repeat containing nuclear envelope protein 1 in humans. It has been reported that Nesprin 1 plays a role in Golgi organization and muscle cell differentiation, among other functions. Structurally, the SYNE1 protein is 8797 amino acid residues in length and 1011.1 kilodaltons in mass. However, as many as 12 protein isoforms have been identified. It is localized to the nucleus and cytoplasm of the cell. In terms of tissue specificity, it is reported to be expressed in HeLa, A431, A172 and HaCaT cells. Other names for this target antigen include 8B, AMC3, and AMCM.
The detection range for different Nesprin 1 ELISA kits can vary, with some assays measuring target concentrations as low as 20 ng/L and as high as 20 ng/mL. Click on the following ELISA kits for more detailed information, including target reactivity and assay sensitivity.