Anti-INSRR antibodies are used in the immunodetection of the protein insulin receptor related receptor. In humans, the canonical protein has a reported length of 1297 amino acid residues and a mass of 143.7 kDa. Its subcellular localization is in the membrane. A member of the Tyr protein kinase protein family, INSRR is a known receptor with tyrosine-protein kinase activity. Post-translational modifications have been described, including phosphorylation and glycosylation. The INSRR marker can be used to identify Type B Intercalated Cells.* Synonyms for this target antigen include insulin receptor-related protein, IR-related receptor, and IRR. INSRR gene orthologs have been reported in the mouse, rat, bovine, frog, chimpanzee and chicken species. A number of INSRR antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. ELISA and Immunohistochemistry are also common applications.
*HuBMAP Human Reference Atlas v1.4