Anti-TUBB8 antibodies are used in the immunodetection of the protein tubulin beta 8 class VIII. In humans, the canonical protein has a reported length of 444 amino acid residues and a mass of 49.8 kDa. Its subcellular localization is in the cytoplasm. It is noted to be expressed at a high level in oocytes, at different stages of development. A member of the Tubulin protein family, TUBB8 is known to be involved with cytoskeleton organization and the cell cycle. Post-translational modifications have been described, including phosphorylation. The TUBB8 gene has been associated with the disease, Oocyte maturation defect. Synonyms for this target antigen include tubulin beta-8 chain and HSA10p15 beta-tubulin 4Q. TUBB8 gene orthologs have been reported in the mouse, rat and chimpanzee species. Over 300 citations in the literature describe the use of TUBB8 antibodies in research. Western Blot is a widely used application for these antibodies. Immunocytochemistry and Immunohistochemistry are also common applications.