Anti-C2 antibodies are used in the immunodetection of the protein complement C2. In humans, the canonical protein has a reported length of 752 amino acid residues and a mass of 83.3 kDa. It has been described to be a secreted protein. Up to 3 different isoforms have been reported for this protein. A member of the Peptidase S1 protein family, C2 is reported to be a Component C2, which is part of the classical pathway of the complement system is cleaved by activated factor C1 into two fragments: C2b and C2a. Post-translational modifications have been described, including glycosylation. Synonyms for this target antigen include CO2, C3/C5 convertase, complement component 2, complement component C2, and ARMD14. C2 gene orthologs have been reported in the mouse, rat, bovine, frog, chimpanzee and chicken species. A number of C2 antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. In addition, ELISA is also a common application.