Anti-IRF1 antibodies are used in the immunodetection of the protein interferon regulatory factor 1. In humans, the canonical protein has a reported length of 325 amino acid residues and a mass of 36.5 kDa. Its subcellular localization is in the nucleus and cytoplasm. It is notably widely expressed in many tissue types. A member of the IRF protein family, IRF1 is a reported transcriptional regulator which displays a remarkable functional diversity in the regulation of cellular responses. Post-translational modifications have been described, including ubiquitination, sumoylation and phosphorylation. The IRF1 gene has been associated with the disease, Gastric cancer. Synonyms for this target antigen include MAR. IRF1 gene orthologs have been reported in the mouse, rat, bovine, frog, chimpanzee and chicken species. Over 290 citations in the literature describe the use of IRF1 antibodies in research. Western Blot is a widely used application for these antibodies. In addition, Immunohistochemistry is also a common application.