Anti-F2RL1 antibodies are used in the immunodetection of the protein F2R like trypsin receptor 1. In humans, the canonical protein has a reported length of 397 amino acid residues and a mass of 44.1 kDa. Its subcellular localization is in the cell membrane. It is found to be widely expressed in tissues with especially high levels in the pancreas, liver, kidney, small intestine, and colon. A member of the G-protein coupled receptor 1 protein family, F2RL1 is a known receptor for trypsin and trypsin-like enzymes coupled to G proteins. Synonyms for this target antigen include PAR2, proteinase-activated receptor 2, G-protein coupled receptor 11, coagulation factor II (thrombin) receptor-like 1, protease-activated receptor 2, and GPR11. F2RL1 gene orthologs have been reported in the mouse, rat, bovine, frog, chimpanzee and chicken species. Over 100 citations in the literature describe the use of F2RL1 antibodies in research. Western Blot and Immunohistochemistry are common applications for these antibodies.