Anti-IKKalpha antibodies are used in antigen-specific immunodetection in biological samples. The target IKKalpha is a known alias name of the protein component of inhibitor of nuclear factor kappa B kinase complex, encoded by the CHUK gene in humans. This 745-amino acid residue protein is reported to be a serine kinase that plays an essential role in the NF-kappa-B signaling pathway which is activated by multiple stimuli such as inflammatory cytokines, bacterial or viral products, DNA damages or other cellular stresses. It is localized to the nucleus and cytoplasm of the cell and features ubiquitinated, acetylated and phosphorylated post-translational modifications. In terms of tissue expression, it is widely expressed across many tissue types. Other synonyms for IKKalpha include BPS2, IKBKA, and IKK-alpha. Western Blot is the most common application for the IKKalpha antibodies listed below. ELISA and Immunohistochemistry are also common applications.