Anti-SLC5A11 antibodies are used in the immunodetection of the protein solute carrier family 5 member 11. In humans, the canonical protein has a reported length of 675 amino acid residues and a mass of 74 kDa. Its subcellular localization is in the cell membrane. Up to 6 different isoforms have been reported for this protein. It is reported to be highly expressed in the heart, skeletal muscle, kidney, liver and placenta. A member of the Sodium:solute symporter (SSF) (TC 2.A.21) protein family, SLC5A11 is reported to be involved in sodium-dependent cotransport of myo-inositol (MI) with a Na(+):MI stoichiometry of 2:1.
The SLC5A11 marker can be used to identify Brain Oligodendrocyte Precursor Cells, Brain Oligodendrocytes, Hypothalamus Oligodendrocytes, Proximal Tubule Segment 2 Epithelial Cells, and Proximal Tubule Segment 3 Epithelial Cells.* Synonyms for this target antigen include Na(+)/myo-inositol cotransporter 2, homolog of rabbit KST1, putative sodium-coupled cotransporter RKST1, sodium-dependent glucose cotransporter, and sodium/myo-inositol cotransporter 2. SLC5A11 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species.
*HuBMAP Human Reference Atlas v1.4