Anti-Interleukin 2 antibodies are used for the immunodetection of the protein encoded by the IL2 gene. In humans, the canonical protein has a reported length of 153 amino acid residues and a mass of 17.6 kDa. It is known to be a secreted protein. A member of the IL-2 protein family, it is known to be involved with adaptive immune responses and cell adhesion. Post-translational modifications have been described, including glycosylation.
The interleukin 2 marker can be used to characterize CD4 Memory T Cells and Effector Memory CD45RA CD4 T Cells.* Other names for this target antigen include lymphokine, T cell growth factor, aldesleukin, involved in regulation of T-cell clonal expansion, and TCGF. Gene orthologs have been identified in the mouse, rat, bovine, chimpanzee and chicken species. Over 2000 citations in the literature describe the use of Interleukin 2 antibodies in research. ELISA is a widely used application for these antibodies. In addition, Western Blot is also a common application.
*HuBMAP Human Reference Atlas v1.4