Anti-COPB1 antibodies are used in the immunodetection of the protein COPI coat complex subunit beta 1. In humans, the canonical protein has a reported length of 953 amino acid residues and a mass of 107.1 kDa. Its subcellular localization is in the cell membrane, cytoplasmic vesicles, ER, Golgi, and cytoplasm. It is notably widely expressed in many tissue types. COPB1 is known to be involved with Golgi transport and intracellular protein transport. The COPB1 gene has been associated with the disease, Baralle-Macken syndrome. Synonyms for this target antigen include COPB, coatomer subunit beta, beta coat protein, beta-cop, coatomer protein complex subunit beta 1, and BARMACS. COPB1 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Over 70 citations in the literature describe the use of COPB1 antibodies in research. Western Blot is a widely used application for these antibodies. ELISA, Immunofluorescence, and Immunohistochemistry are also common applications.