Anti-beta COP antibody ab2899 from Abcam

Product Specs
ItemAnti-beta COP antibody
CompanyAbcam
Price Pricing Info Supplier Page View Company Product Page
Catalog Numberab2899
Antibody TypePrimary
ApplicationsImmunocytochemistry/ Immunofluorescence, Western blot
Quantity100 UL
HostRabbit
IsotypeIgG
ClonalityPolyclonal
Conjugate/TagUnconjugated
Concentration4.4 mg/ml
Gene NameCOPB1
ReactivityHuman, Mouse, Rat
Targetbeta COP

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Abcam

Discovery Drive

Cambridge Biomedical Campus

Cambridge CB2 0AX

United Kingdom

Phone: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600

Company Profile

Website: http://www.abcam.com

(1) A single C-terminal residue controls SARS-CoV-2 spike trafficking and incorporation into VLPsNat CommunDecember 15, 2023Debajit Dey, Enya Qing, Yanan He, Yihong Chen, Benjamin Jennings, Whitaker Cohn, Suruchi Singh, Lokesh Gakhar, Nicholas J. Schnicker, Brian G. Pierce, et al.No. A3854; Sigma-Aldrich, USA; 1:10,000 dilution); rabbit anti-β-COPI polyclonal antibody (Cat. No. ab2899; Abcam, USA; 1:1000 dilution); rabbit anti-giantin polyclonal antibody (Cat. No. 924302; BioLegend,

(2) Zinc homeostasis governed by Golgi-resident ZnT family members regulates ERp44-mediated proteostasis at the ER-Golgi interfaceNature CommunicationsMay 9, 2023Yuta Amagai, Momo Yamada, Toshiyuki Kowada, Tomomi Watanabe, Yuyin Du, Rong Liu, Satoshi Naramoto, Satoshi Watanabe, Junko Kyozuka, Tiziana Anelli, et al.(1:2000 for IF), GM130 (PM061; MBL) (1:2000 for IF), SEC24C (HPA040196, SIGMA) (1:500 for IF), βCOP (ab2899, Abcam) (1:1000 for IF), a DDDDK-tag (PM020, MBL) (1: 4000 for IF), and ZnT6 (HPA057328; Atlas Antibodies)

(3) Identification of global inhibitors of cellular glycosylationNature communicationsFebruary 20, 2023Sørensen DM, Büll C, Madsen TD, Lira-Navarrete E, Clausen TM, Clark AE, Garretson AF, Karlsson R, Pijnenborg JFA, Yin X, et al.receptor (PA1-510A, Thermo Fisher), Giantin (mouse: ab24586, Abcam; rabbit: ab80864, Abcam), bCOP (ab2899, Abcam), GM130 (610822, BD-Biosciences), Tubulin (T6199, Sigma), AcTub (T7451, Sigma) or TGN46 (ab50595,

(4) Dominant ARF3 variants disrupt Golgi integrity and cause a neurodevelopmental disorder recapitulated in zebrafishNature communicationsNovember 11, 2022Fasano G, Muto V, Radio FC, Venditti M, Mosaddeghzadeh N, Coppola S, Paradisi G, Zara E, Bazgir F, Ziegler A, et al.overnight for 1 h at 4 °C. These antibodies were used: rabbit polyclonal anti-ß COP (1:2000, Abcam, ab2899), rabbit monoclonal anti-Rab5 (1:200, Cell Signaling, 3547S) and mouse monoclonal anti-LAMP-2 (1:200,

(5) Interactions among key residues regulate mammalian odorant receptor traffickingThe FASEB JournalAugust 5, 2022Rui Xu, Xiaojing Cong, Qian Zheng, Lun Xu, Mengjue J. Ni, Claire A. de March, Hiroaki Matsunami, Jérôme Golebiowski, Minghong Ma, Yiqun Yuwith primary antibodies including rabbit anti-Calnexin (#ab75801, 1:100, Abcam) or rabbit anti-βCOP (#ab2899, 1:100, Abcam) for 1 h at room temperature. After washed with PBS, the cells were incubated with secondary

(6) Tankyrase-1-mediated degradation of Golgin45 regulates glycosyltransferase trafficking and protein glycosylation in Rab2-GTP-dependent mannerCommunications biologyDecember 7, 2021Yue X, Tiwari N, Zhu L, Ngo HDT, Lim JM, Gim B, Jing S, Wang Y, Qian Y, Lee I.15293-1-AP, Proteintech), anti-ARF1 (1:1000 for WB, 10790-1-AP, Proteintech), anti-β-COP (1:3000 for WB, ab2899, Abcam), anti-γ-COP (1:1000 for WB, sc-393615, Santa cruz), anti-COG4 (1:3000 for WB, ab154795, Abcam),

(7) Phosphorylation and Pin1 binding to the LIC1 subunit selectively regulate mitotic dynein functionsThe Journal of cell biologyDecember 6, 2021Kumari A, Kumar C, Pergu R, Kumar M, Mahale SP, Wasnik N, Mylavarapu SVS.LAMP1 (Sigma-Aldrich; L1418), γ-tubulin (Abcam; ab11316), mCherry (Abcam; ab167453), β-COP (Abcam; ab2899), BICD2 (Abcam; ab117818), p50 (BD Biosciences; 611002), and CREST (Antibodies Inc.). The following

(8) ACBD3 modulates KDEL receptor interaction with PKA for its trafficking via tubulovesicular carrierBMC biologySeptember 7, 2021Yue X, Qian Y, Zhu L, Gim B, Bao M, Jia J, Jing S, Wang Y, Tan C, Bottanelli F, et al.anti-GM130 (610822, BD bioscience), anti-Golgin97 (#13192, Cell Signaling Technology), anti-β-COP (ab2899, Abcam), anti-γ-COP (sc-393615, Santa cruz), anti-ARFGAP1 (ab204405, Abcam), anti-ARFGAP2 (ab133768,

(9) A weak COPI binding motif in the cytoplasmic tail of SARS-CoV-2 spike glycoprotein is necessary for its cleavage, glycosylation, and localizationFEBS lettersJuly 1, 2021Jennings BC, Kornfeld S, Doray B.(Cat #05‐170) from Millipore‐Sigma (St. Louis, MO, USA), anti‐β‐COP rabbit polyclonal antibody (Cat #ab2899) from Abcam (Cambridge, MA, USA), anti‐δ‐COP rabbit polyclonal antibody (Cat #PA5‐21484) from Life Technologies,

(10) Biallelic variants in COPB1 cause a novel, severe intellectual disability syndrome with cataracts and variable microcephalyGenome medicineFebruary 25, 2021Macken WL, Godwin A, Wheway G, Stals K, Nazlamova L, Ellard S, Alfares A, Aloraini T, AlSubaie L, Alfadhel M, et al.non-fat milk powder/PBS and immunostained with rabbit anti giantin (ab37266, Abcam) and mouse anti-β-COP (ab2899, Abcam) or rabbit anti SERPINH1 (HPA029198, Atlas Antibodies) and mouse anti-c myc antibody (clone 9E10,

(11) Trio cooperates with Myh9 to regulate neural crest-derived craniofacial developmentTheranosticsJanuary 1, 2021Guo S, Meng L, Liu H, Yuan L, Zhao N, Ni J, Zhang Y, Ben J, Li YP, Ma J.were incubated in a medium with 5% FBS for 24 h, and then fixed in 4% PFA, and incubated with GM130 (#ab2899, Abcam) at 4 ºC overnight. The next day, the cells were incubated with secondary antibodies to recognize

(12) Activity of the SNARE Protein SNAP29 at the Endoplasmic Reticulum and Golgi ApparatusFrontiers in cell and developmental biologyJanuary 1, 2021Morelli E, Speranza EA, Pellegrino E, Beznoussenko GV, Carminati F, Garré M, Mironov AA, Onorati M, Vaccari T.particular, for immune EM gold-labeling, cryosections were stained with the anti-β COP antibody 1:100 (Abcam ab2899) and anti-GFP (Abcam ab6556) for 2 h, washed six times with 0.1% bovine serum albumin in phosphate-buffered

(13) CHIP ubiquitylates NOXA and induces its lysosomal degradation in response to DNA damageCell death & diseaseSeptember 10, 2020Albert MC, Brinkmann K, Pokrzywa W, Günther SD, Krönke M, Hoppe T, Kashkar H.#ab56783-100); anti-NOXA (clone 114C307 Merck #OP180); anti-Sec23 (Abcam #ab87352); anti-Cop1β (Abcam #ab2899); anti-EEA1 (clone C45B10, Cell Signaling #3288P); anti-APPL (clone D83H4, Cell Signaling #38588); anti-Syntaxin6

(14) Role of Gate-16 and Gabarap in Prevention of Caspase-11-Dependent Excess Inflammation and Lethal Endotoxic ShockFrontiers in immunologyJanuary 1, 2020Sakaguchi N, Sasai M, Bando H, Lee Y, Pradipta A, Ma JS, Yamamoto M.obtained from Millipore. TOM20 (11802-1-AP) was obtained from Proteintech. Antibody against β-COP (ab2899) were purchased from Abcam. Anti-Aim2 (ab93015) was purchased from Abcam. Anti-NLRC4 (06-1125) was purchased

(15) Adult stem cell deficits drive Slc29a3 disorders in miceNature communicationsJuly 3, 2019Nair S, Strohecker AM, Persaud AK, Bissa B, Muruganandan S, McElroy C, Pathak R, Williams M, Raj R, Kaddoumi A, et al.Santa Cruz Biotechnology (Santa Cruz, CA). Anti-F4/80 antibody (ab6640; 1:1000 dilution) and anti-β-COP antibody (ab2899; 1:200 dilution) from were obtained from Abcam. Horseradish peroxidase-conjugated anti-rabbit IgG, anti-mouse

(16) Hepatic Sdf2l1 controls feeding-induced ER stress and regulates metabolismNature communicationsFebruary 27, 2019Sasako T, Ohsugi M, Kubota N, Itoh S, Okazaki Y, Terai A, Kubota T, Yamashita S, Nakatsukasa K, Kamura T, et al.(PM060, 1:1000) from MBL; anti-insulin/proinsulin (ab8304, for immunoprecipitation), and anti-βCOP (ab2899, 1:1000) from Abcam; anti-FLAG (M2, 1:2500) from Sigma; anti-tubulinα (RB-9281, 1:1000) from Thermo

(17) Highly conserved motifs within the large Sec7 ARF guanine nucleotide exchange factor GBF1 target it to the Golgi and are critical for GBF1 activityAmerican journal of physiology. Cell physiologyJune 1, 2018Pocognoni CA, Viktorova EG, Wright J, Meissner JM, Sager G, Lee E, Belov GA, Sztul E.NBP243575, Novus), polyclonal anti-GFP (catalog no. ab290, Abcam), polyclonal anti-␤-COP (catalog no. ab2899, Abcam), monoclonal anti-GM130 (catalog no. 610823, BD Transduction Laboratories). Secondary anti-mouse

(18) Podosome assembly is controlled by the GTPase ARF1 and its nucleotide exchange factor ARNOThe Journal of cell biologyJanuary 2, 2017Rafiq NB, Lieu ZZ, Jiang T, Yu CH, Matsudaira P, Jones GE, Bershadsky AD.EMD Millipore); anti–α-tubulin (dilution 1:3,000; T6199; Sigma-Aldrich); anti-βCOP (dilution 1:1,000; ab2899; Abcam); anti-HA (dilution 1:1,000; 2367; Cell Signaling Technology); anti-Cdc42 (dilution 1:1,000;

(19) CCDC115 Deficiency Causes a Disorder of Golgi Homeostasis with Abnormal Protein GlycosylationAmerican journal of human geneticsFebruary 4, 2016Jansen JC, Cirak S, van Scherpenzeel M, Timal S, Reunert J, Rust S, Pérez B, Vicogne D, Krawitz P, Wada Y, et al.

(20) TMEM199 Deficiency Is a Disorder of Golgi Homeostasis Characterized by Elevated Aminotransferases, Alkaline Phosphatase, and Cholesterol and Abnormal GlycosylationAmerican journal of human geneticsFebruary 4, 2016Jansen JC, Timal S, van Scherpenzeel M, Michelakakis H, Vicogne D, Ashikov A, Moraitou M, Hoischen A, Huijben K, Steenbergen G, et al.

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Anti-beta COP antibody from Abcam

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Anti-beta COP antibody from Abcam

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