Anti-AXIN1 antibodies are used in the immunodetection of the protein axin 1. In humans, the canonical protein has a reported length of 862 amino acid residues and a mass of 95.6 kDa. Its subcellular localization is in the cell membrane, nucleus, and cytoplasm. Up to 2 different isoforms have been reported for this protein. It is ubiquitously expressed across many tissue types. AXIN1 is a known component of the beta-catenin destruction complex required for regulating CTNNB1 levels through phosphorylation and ubiquitination, and modulating Wnt-signaling. Synonyms for this target antigen include PPP1R49, axis inhibition protein 1, axis inhibitor 1, fused, mouse, homolog of, protein phosphatase 1, regulatory subunit 49, and AXIN. AXIN1 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Over 220 citations in the literature describe the use of AXIN1 antibodies in research. Western Blot is a widely used application for these antibodies. ELISA, Immunofluorescence, and Immunohistochemistry are also common applications.