GRHL2 is a symbol for the gene, Grainyhead-like transcription factor 2, in humans. Other names include: Grainyhead-like protein 2 homolog; Brother of mammalian grainyhead; Transcription factor CP2-like 3; BOM; DFNA28; ECTDS; TFCP2L3; grainyhead-like 2 (Drosophila). The encoded protein has an amino acid length of 625 and a mass of 71.1 kDa. Other isoforms may exist. GRHL2 is a member of the Grh/CP2 family, Grainyhead subfamily. This gene shares homology with other species, including: Frog.