Anti-PTGS2 antibodies are used in the immunodetection of the protein prostaglandin-endoperoxide synthase 2. In humans, the canonical protein has a reported length of 604 amino acid residues and a mass of 69 kDa. Its subcellular localization is in the nucleus, ER, and membrane. It is notably expressed in the seminal vesicle, rectum, gallbladder, duodenum, and appendix. A member of the Prostaglandin G/H synthase protein family, PTGS2 is known to be involved with pathways of aging and angiogenesis. Post-translational modifications have been described, including acetylation and glycosylation. Synonyms for this target antigen include COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2, prostaglandin G/H synthase 2, and COX-2. PTGS2 gene orthologs have been reported in the mouse, rat, bovine, frog, chimpanzee and chicken species. Over 1900 citations in the literature describe the use of PTGS2 antibodies in research. Western Blot is a widely used application for these antibodies. Immunofluorescence and Immunohistochemistry are also common applications.