Anti-XPA antibodies are used in the immunodetection of the protein XPA, DNA damage recognition and repair factor. In humans, the canonical protein has a reported length of 273 amino acid residues and a mass of 31.4 kDa. Its subcellular localization is in the nucleus. It is reported to be expressed in various cell lines and in skin fibroblasts. A member of the XPA protein family, XPA is known to be involved in DNA excision repair. Post-translational modifications have been described, including ubiquitination and phosphorylation. Synonyms for this target antigen include XPAC, DNA repair protein complementing XP-A cells, xeroderma pigmentosum group A-complementing protein, xeroderma pigmentosum, complementation group A, and XP1. XPA gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Over 60 citations in the literature describe the use of XPA antibodies in research. Western Blot is a widely used application for these antibodies. ELISA and Immunohistochemistry are also common applications.