Anti-XPA antibody [5F12] ab65963 from Abcam

Product Specs
ItemAnti-XPA antibody [5F12]
CompanyAbcam
Price Supplier Page View Company Product Page
Catalog Numberab65963
Antibody TypePrimary
ClonalityMonoclonal
HostMouse, Nude mouse
ApplicationsELISA, Immunocytochemistry/ Immunofluorescence, Inhibition Assay, Western blot
Clone5F12
IsotypeIgG2b
Quantity100 UL
Concentration1 mg/ml
Gene NameXPA
ValidationKnockOut Validated
ReactivityHuman
TargetXPA
Conjugate/TagUnconjugated

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Abcam

Discovery Drive

Cambridge Biomedical Campus

Cambridge CB2 0AX

United Kingdom

Phone: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600

Company Profile

Website: http://www.abcam.com

(1) Ubiquitin signaling and the proteasome drive human DNA–protein crosslink repairNucleic Acids ResearchDecember 11, 2023Maram Essawy, Lisa Chesner, Duha Alshareef, Shaofei Ji, Natalia Tretyakova, Colin Campbellab14707, Lot #: APN17146-2-1-S). Rabbit polyclonal anti-XPA primary antibody was purchased from Abcam (ab65963) and used at a 1:2000 dilution. HRP-conjugated goat-anti rabbit secondary antibody was purchased from

(2) XPA is susceptible to proteolytic cleavage by cathepsin L during lysis of quiescent cellsDNA Repair (Amst)January 1, 2022Saman Khan, William Cvammen, Nadeen Anabtawi, Jun-Hyuk Choi, Michael G. Kempanalyzed by western blotting with four different anti-XPA antibodies (#1, Santa Cruz sc-28353; #2, Abcam ab65963; #3, Cell Signaling #14607; and #4, Santa Cruz sc-853). (B) XPA protein expression was detected in lysates

(3) The Bloom syndrome complex senses RPA-coated single-stranded DNA to restart stalled replication forksNature communicationsJanuary 26, 2021Shorrocks AK, Jones SE, Tsukada K, Morrow CA, Belblidia Z, Shen J, Vendrell I, Fischer R, Kessler BM, Blackford AN.1/1000), TOP3A (14525-1-1AP, Proteintech, 1/1000), TOPBP1 (A300-111A, Bethyl Laboratories, 1/2000), XPA (ab65963, Abcam, 1/2000). Uncropped and unprocessed scans of all blots can be found in the Source Data file associated

(4) β-HPV 8E6 Attenuates ATM and ATR Signaling in Response to UV DamagePathogens (Basel, Switzerland)November 26, 2019Snow JA, Murthy V, Dacus D, Hu C, Wallace NA.Hampton, NH), CDK2 (78B2) (2546S, Cell Signaling), pXPA (Ser196) (PA5-64730, Thermo Fisher), XPA (5F12) (ab65963, Abcam), RAD18 (ab57447, Abcam), UB. PCNA (Lys164) (D5C7P) (13439S, Cell Signaling), PCNA (PC10) (2586S,

(5) Inorganic arsenic inhibits the nucleotide excision repair pathway and reduces the expression of XPCDNA Repair (Amst.)April 1, 2017Nathaniel Holcomb, Mamta Goswami, Sung Gu Han, Tim Scott, John D’Orazio, David K. Orren, C. Gary Gairola, Isabel MellonXPA in IMR-90 cells, sc-28353 (Santa Cruz Biotechnology), and for XPA in mouse keratinocytes cells, ab65963 (Abcam). Both cell types were treated with a range of arsenite concentrations or mock treated as described.

(6) Targeting DNA repair with aphidicolin sensitizes primary chronic lymphocytic leukemia cells to purine analogsOncotargetJune 21, 2016Eliza Starczewska, Maxime Beyaert, Lucienne Michaux, Marie-Christiane Vekemans, Pascale Saussoy, Vanesa Bol, Ainhoa Arana Arana Echarri, Caroline Smal, Eric Van Den Neste, Françoise Bontemps(#9665S) and anti-caspase-9 (#9502S) from Cell Signaling Technologies (Beverly, MA, USA); anti-XPA (ab65963) and anti-lamin B1 (ab16048) from Abcam (Cambridge, UK); Alexa Fluor 488 Mouse anti-H2AX (pS139) from

(7) Base and Nucleotide Excision Repair of Oxidatively Generated Guanine Lesions in DNAThe Journal of biological chemistryMarch 4, 2016Vladimir Shafirovich, Konstantin Kropachev, Thomas Anderson, Zhi Liu, Marina Kolbanovskiy, Brooke D Martin, Kent Sugden, Yoonjung Shim, Xuejing Chen, Jung-Hyun Min, Nicholas E Geacintov

(8) An inverse switch in DNA base excision and strand break repair contributes to melphalan resistance in multiple myeloma cellsPloS oneJanuary 1, 2013Sousa MM, Zub KA, Aas PA, Hanssen-Bauer A, Demirovic A, Sarno A, Tian E, Liabakk NB, Slupphaug G.µg/mL), MSH2 (ab16833-50, 1 µg/mL) DNA ligase 1 (ab615, 1∶3000), DNA ligase 3 (ab587, 2 µg/mL) and XPA (ab65963, 1 µg/mL), MPG (ab55461, 1 µg/mL) from Abcam; pATM (4526S, 1∶1000), pATR (2853, 1∶1000), pChk2 (2661,

(9) Differences in repair of DNA cross-links between lymphocytes and epithelial tumor cells from colon cancer patients measured in vitro with the comet assayClinical cancer research : an official journal of the American Association for Cancer ResearchSeptember 1, 2009Mercedes Herrera, Gemma Dominguez, Jose M Garcia, Cristina Peña, Carmen Jimenez, Javier Silva, Vanesa Garcia, Irene Gomez, Raquel Diaz, Paloma Martin, Felix Bonilla

(10) A blood group-related polymorphism of CD44 abolishes a hyaluronan-binding consensus sequence without preventing hyaluronan bindingThe Journal of biological chemistryMarch 22, 1996M J Telen, M Udani, M K Washington, M C Levesque, E Lloyd, N Rao

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Anti-XPA antibody [5F12] from Abcam

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Anti-XPA antibody [5F12] from Abcam

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