Anti-TRAF3 antibodies are used in the immunodetection of the protein TNF receptor associated factor 3. In humans, the canonical protein has a reported length of 568 amino acid residues and a mass of 64.5 kDa. Its subcellular localization is in the mitochondria and cytoplasm. Up to 2 different isoforms have been reported for this protein. A member of the TNF receptor-associated factor protein family, TRAF3 is known to be involved with the apoptotic pathway and viral immune response. Post-translational modifications have been described, including ubiquitination and protein cleavage. The TRAF3 gene has been associated with the disease, Encephalopathy. Synonyms for this target antigen include CAP-1 and CAP1. TRAF3 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Over 120 citations in the literature describe the use of TRAF3 antibodies in research. Western Blot is a widely used application for these antibodies. ELISA, Immunofluorescence, and Immunohistochemistry are also common applications.