Anti-APOA1 antibodies are used in the immunodetection of the protein apolipoprotein A1. In humans, the canonical protein has a reported length of 267 amino acid residues and a mass of 30.8 kDa. It has been described to be a secreted protein. It is notably expressed in the appendix. A member of the Apolipoprotein A1/A4/E protein family, APOA1 is known to participate in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). Synonyms for this target antigen include apo(a), apolipoprotein A-I, apo-AI, epididymis secretory sperm binding protein, and HPALP2. APOA1 gene orthologs have been reported in the mouse, rat, bovine, chimpanzee and chicken species. Over 250 citations in the literature describe the use of APOA1 antibodies in research. Western Blot is a widely used application for these antibodies. ELISA and Immunohistochemistry are also common applications.