Anti-LY6K antibodies are used in the immunodetection of the protein lymphocyte antigen 6 family member K. In humans, the canonical protein has a reported length of 165 amino acid residues and a mass of 18.7 kDa. Its subcellular localization is in the cell membrane, cytoplasmic vesicles, cytoplasm, and is secreted. Up to 2 different isoforms have been reported for this protein. It is notably expressed in the testis. LY6K is known to be required for sperm migration into the oviduct and male fertility by controlling binding of sperm to zona pellucida (By similarity). Post-translational modifications have been described, including glycosylation. Synonyms for this target antigen include HSJ001348, URLC10, lymphocyte antigen 6K, cancer/testis antigen 97, lymphocyte antigen 6 complex, locus K, and CT97. LY6K gene orthologs have been reported in the mouse, rat and chimpanzee species. A number of LY6K antibodies have been mentioned in research publications and have associated citations. ELISA and Western Blot are common applications for these antibodies.