Anti-ME1 antibodies are used in the immunodetection of the protein malic enzyme 1. In humans, the canonical protein has a reported length of 572 amino acid residues and a mass of 64.2 kDa. Its subcellular localization is in the cytoplasm. Up to 2 different isoforms have been reported for this protein. It is reported to be expressed in all tissues tested including liver, placenta and white adipose tissue. A member of the Malic enzymes protein family, ME1 is known to catalyze the oxidative decarboxylation of (S)-malate in the presence of NADP(+) and divalent metal ions, and decarboxylation of oxaloacetate. Synonyms for this target antigen include MES, NADP-dependent malic enzyme, Malic enzyme, cytoplasmic, NADP-ME, malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)), and HUMNDME. ME1 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. A number of ME1 antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. ELISA and Immunohistochemistry are also common applications.