Anti-TNNI3 antibodies are used in the immunodetection of the protein troponin I3, cardiac type. In humans, the canonical protein has a reported length of 210 amino acid residues and a mass of 24 kDa. It is notably expressed in the heart muscle and testis. A member of the Troponin I protein family, TNNI3 is known to be involved with cardiac tissue development and the regulation of intracellular calcium. Post-translational modifications have been described, including phosphorylation. The TNNI3 gene has been associated with the disease, Cardiomyopathy. Synonyms for this target antigen include CMD2A, CMH7, RCM1, TNNC1, cTnI, and CMD1FF. TNNI3 gene orthologs have been reported in the mouse, rat, bovine, frog and chimpanzee species. Over 520 citations in the literature describe the use of TNNI3 antibodies in research. Western Blot is a widely used application for these antibodies. ELISA and Immunohistochemistry are also common applications.