Anti-CD207 molecule antibodies are used for the immunodetection of the protein encoded by the CD207 gene. In humans, the canonical protein has a reported length of 328 amino acid residues and a mass of 36.7 kDa. Its subcellular localization is in the membrane. It is noted to be involved in viral immune response. Post-translational modifications have been described, including glycosylation.
The CD207 molecule marker can be used to characterize Langerhans Cells.* Other names for this target antigen include C-type lectin domain family 4 member K, C-type lectin domain family 4, member K, CD207 antigen, langerin, CD207 molecule, langerin, Langerhans cell specific c-type lectin, and CLEC4K. Gene orthologs have been identified in the mouse, rat, bovine and chimpanzee species. Over 420 citations in the literature describe the use of CD207 molecule antibodies in research. Western Blot is a widely used application for these antibodies. ELISA, Flow Cytometry, and Immunohistochemistry are also common applications.
*HuBMAP Human Reference Atlas v1.4