Langerin/CD207 Antibody AF2088 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemLangerin/CD207 Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberAF2088
NCBI Gene AliasesCLEC4K
ApplicationsWestern Blot, Immunohistochemistry
TargetLangerin/CD207
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
IsotypeIgG
ReactivityHuman
Conjugate/TagUnconjugated
Quantity100 ug (also 25 ug)
HostGoat
NCBI Full Gene NameCD207 molecule
ClonalityPolyclonal
ImmunogenMouse myeloma cell line NS0-derived recombinant human Langerin/CD207, Tyr64-Pro328, Accession # Q9UJ71
ConcentrationLYOPH
PurityImmunogen affinity purified
Brand/TrademarkR&D Systems, a Bio-Techne Brand
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Unconjugated

Specificity: Detects human Langerin/CD207 in direct ELISAs and Western blots

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) CGRP inhibits human Langerhans cells infection with HSV by differentially modulating specific HSV-1 and HSV-2 entry mechanismsMucosal immunologyApril 1, 2022Cohen E, Mariotton J, Rozenberg F, Sams A, van Kuppevelt TH, Barry Delongchamps N, Zerbib M, Bomsel M, Ganor Y.

(2) Herpes Simplex Virus type 1 infects Langerhans cells and the novel epidermal dendritic cell, Epi-cDC2s, via different entry pathwaysPLoS pathogensApril 1, 2021Bertram KM, Truong NR, Smith JB, Kim M, Sandgren KJ, Feng KL, Herbert JJ, Rana H, Danastas K, Miranda-Saksena M, et al.

(3) The Essential Role of anxA2 in Langerhans Cell Birbeck Granules FormationCellsApril 15, 2020Thornton SM, Samararatne VD, Skeate JG, Buser C, Lühen KP, Taylor JR, Da Silva DM, Kast WM.

(4) Identification of HIV transmitting CD11c⁺ human epidermal dendritic cellsNature communicationsJune 21, 2019Bertram KM, Botting RA, Baharlou H, Rhodes JW, Rana H, Graham JD, Patrick E, Fletcher J, Plasto TM, Truong NR, et al.

(5) TRIM5α Restricts Flavivirus Replication by Targeting the Viral Protease for Proteasomal DegradationCell reportsJune 11, 2019Chiramel AI, Meyerson NR, McNally KL, Broeckel RM, Montoya VR, Méndez-Solís O, Robertson SJ, Sturdevant GL, Lubick KJ, Nair V, et al.cyclophilin A (Enzo, #BML-SA296-0100), cyclophilin B (Thermo Scientific, #PA1-027A), langerin (R&D Systems, #AF2088) and DC-SIGN (BD Biosciences, #551186). Immunoprecipitation (IP) and Western Blot Analysis 293 cells

(6) Chemokine Levels in the Penile Coronal Sulcus Correlate with HIV-1 Acquisition and Are Reduced by Male Circumcision in Rakai, UgandaPLoS pathogensNovember 1, 2016Prodger JL, Gray RH, Shannon B, Shahabi K, Kong X, Grabowski K, Kigozi G, Nalugoda F, Serwadda D, Wawer MJ, et al.

(7) Stable CD4 Expression and Local Immune Activation in the Ectocervical Mucosa of HIV-Infected WomenThe Journal of ImmunologyOctober 1, 2013Taha Hirbod et al.Laboratories, Burlingame, CA). Anti-human CD4 (clone) (SK3) (BD Biosciences, Franklin Lakes, NJ), Langerin (AF2088), DC-SIGN (120507) (both from R&D Systems, Minneapolis, MN), MR (19.2) (BD Biosciences), and CCR5 (MC-5)

(8) Plasmacytoid dendritic cells infiltrate the skin in positive tuberculin skin test indurationsThe Journal of investigative dermatologyJanuary 1, 2012Bond E, Liang F, Sandgren KJ, Smed-Sörensen A, Bergman P, Brighenti S, Adams WC, Betemariam SA, Rangaka MX, Lange C, et al.

(9) Detection of Intraepithelial and Stromal Langerin and CCR5 Positive Cells in the Human Endometrium: Potential Targets for HIV InfectionPLoS ONEJune 29, 2011Tove Kaldensjö, Pernilla Petersson, Anna Tolf, Gareth Morgan, Kristina Broliden, Taha Hirbodmonoclonal and polyclonal antibodies were used to detect the immune markers of interest: Langerin (clone: AF2088), DCSIGN (clone: 120507) DLEC (BDCA-2 clone: AF1376) (R&D systems, Minneapolis, MN) MR (clone: 19.2)

(10) HIV-1 replication in Langerhans and interstitial dendritic cells is inhibited by neutralizing and Fc-mediated inhibitory antibodiesJournal of virologyJanuary 1, 2011Peressin M, Holl V, Schmidt S, Decoville T, Mirisky D, Lederle A, Delaporte M, Xu K, Aubertin AM, Moog C.

(11) In situ distribution of HIV-binding CCR5 and C-type lectin receptors in the human endocervical mucosaPloS oneJanuary 1, 2011Hirbod T, Kaldensjö T, Broliden K.anti-human antibodies were used to detect the immune markers of interest: goat anti-Langerin (clone#: AF2088 diluted 1:250), mouse anti-DC-SIGN (clone#: 120507 diluted 1:500), goat anti-DLEC (BDCA-2 clone#: AF1376

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Langerin/CD207 Antibody

Langerin/CD207 Antibody

Langerin/CD207 Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

Citations (11)

Reviews

Langerin/CD207 Antibody from R&D Systems, a Bio-Techne Brand

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