Anti-DVL3 antibodies are used in the immunodetection of the protein dishevelled segment polarity protein 3. In humans, the canonical protein has a reported length of 716 amino acid residues and a mass of 78.1 kDa. Its subcellular localization is in the cytoplasm. Up to 2 different isoforms have been reported for this protein. It is notably widely expressed in many tissue types. A member of the DSH protein family, DVL3 is reported to be involved in signal transduction pathway mediated by multiple Wnt genes. Synonyms for this target antigen include segment polarity protein dishevelled homolog DVL-3, dishevelled 3 (homologous to Drosophila dsh), dishevelled, dsh homolog 3, and DRS3. DVL3 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Over 120 citations in the literature describe the use of DVL3 antibodies in research. Western Blot is a widely used application for these antibodies. ELISA, Immunofluorescence, and Immunohistochemistry are also common applications.