Dvl-3 (4D3) Antibody sc-8027 from Santa Cruz Biotechnology, Inc.

Product Specs
ItemDvl-3 (4D3) Antibody
CompanySanta Cruz Biotechnology, Inc.
Price $316.00Supplier Page View Company Product Page
Catalog Numbersc-8027
Antibody TypePrimary Antibodies
Clone4D3
Reactivitymouse, rat, human
Quantity200 µg/ml
ApplicationsWB, IP
ClonalityMonoclonal
Hostmouse
Conjugate/TagUnconjugated
FormatPurified
NCBI Full Gene Namedishevelled segment polarity protein 3
TargetDvl-3
NCBI Gene AliasesDRS3, b2b2866Clo
IsotypeIgG1

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) A Wnt-induced conformational phospho-switch in DVL3 controls association with Frizzled receptors and Wnt/β-catenin signalingSci AdvMay 15, 2026Miroslav Micka, Jitender Kumar, Petra Paclíková, Zuzana Hayek, Kateřina Hanáková, Cherine Bechara, Hana Plešingerová, Ondrej Šedo, Sara Bologna, Elise Del Nero, et al.imidazole, and 2 mM EDTA was added to the sample. The eluate was incubated with 10 μg of DVL 3 antibody (sc-8027, Santa Cruz Biotechnology) for 1 hour at 4°C and then overnight with Protein G Dynabeads (10004D, Thermo Fisher Scientific

(2) PRICKLE3 protects VANGL proteins from CK1-mediated phosphorylation and RNF43-mediated degradationCommunications BiologyDecember 27, 2025Katarzyna A. Radaszkiewicz, Tomasz W. Radaszkiewicz, Pavla Kolářová, Petra Paclíková, Kristína Gömöryová, Šárka Novotná, Lorena Agostini Maia, Tereza Číhalová, Yao Le, Tomáš Bárta, et al.such as antibody specificity may contribute to variable results; for instance, the anti-DVL3 antibody (sc-8027, Santa Cruz Biotechnology) has been shown to produce different banding patterns depending on the DVL3

(3) Cholesterol-targeting Wnt-β-catenin signaling inhibitors for colorectal cancerNature chemical biologySeptember 1, 2025Sharma A, Zalejski J, Bendre SV, Kavrokova S, Hasdemir HS, Ozgulbas DG, Sun J, Pathmasiri KC, Shi R, Aloulou A, et al.Cell Signaling Technology. Anti-Dvl1 (Cat no. SC-8025,1:1000), anti-Dvl2 (Cat no. SC-390303,1:1000), and anti-Dvl3 (Cat no. SC-8027, 1:1000) were from Santa Cruz Biotechnology and anti-GAPDH (Cat no. PLA0125, 1:5000) from Millipore-Sigma.

(4) Proanthocyanidins inhibited colorectal cancer stem cell characteristics through Wnt/β-catenin signalingEnvironmental toxicologyDecember 1, 2023Chen Y, Yang Z, He X, Zhu W, Wang Y, Li J, Han Z, Wen J, Liu W, Yang Y, et al.

(5) Dishevelled phase separation promotes Wnt signalosome assembly and destruction complex disassemblyJournal of Cell BiologyDecember 5, 2022Kexin Kang, Qiaoni Shi, Xu Wang, Ye-Guang ChenCell Signaling Technology), mouse monoclonal anti-Dvl1 (sc-8025; Santa Cruz Technology), mouse monoclonal anti-Dvl3 (sc-8027; Santa Cruz Technology), mouse monoclonal anti-β-catenin (SC7963; Santa Cruz Technology), rabbit monoclonal

(6) Protein proximity networks and functional evaluation of the casein kinase 1 gamma family reveal unique roles for CK1γ3 in WNT signalingThe Journal of biological chemistryJune 1, 2022Agajanian MJ, Potjewyd FM, Bowman BM, Solomon S, LaPak KM, Bhatt DP, Smith JL, Goldfarb D, Axtman AD, Major MB.catalog no.: ab64829), CK1γ3 (Abcam; catalog no.: ab116310), DVL3 (Santa Cruz Biotechnology; catalog no.: sc-8027), CELSR2 (Cell Signaling Technology; catalog no.: 47061), V5 (Thermo Fisher Scientific; catalog no.:

(7) RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapyeLifeOctober 27, 2021Radaszkiewicz T, Nosková M, Gömöryová K, Vondálová Blanářová O, Radaszkiewicz KA, Picková M, Víchová R, Gybeľ T, Kaiser K, Demková L, et al.RRID:AB_10694060,WB (1:1000) Antibody,DVL-3 (rabbit monoclonal),"Santa Cruz Biotechnology Kaiser et al., 2019",SC-8027; RRID:AB_627434,WB (1:1000) Antibody,Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (rabbit polyclonal),"Cell Signaling Technology

(8) A non-canonical, interferon-independent signaling activity of cGAMP triggers DNA damage response signalingNature communicationsOctober 27, 2021Banerjee D, Langberg K, Abbas S, Odermatt E, Yerramothu P, Volaric M, Reidenbach MA, Krentz KJ, Rubinstein CD, Brautigan DL, et al.

(9) ASPM promotes hepatocellular carcinoma progression by activating Wnt/β-catenin signaling through antagonizing autophagy-mediated Dvl2 degradationFEBS open bioOctober 1, 2021Zhang H, Yang X, Zhu L, Li Z, Zuo P, Wang P, Feng J, Mi Y, Zhang C, Xu Y, et al.

(10) Roles of individual human Dishevelled paralogs in the Wnt signalling pathwaysCellular signallingSeptember 1, 2021Paclíková P, Radaszkiewicz TW, Potěšil D, Harnoš J, Zdráhal Z, Bryja V.

(11) A Norrin/Wnt surrogate antibody stimulates endothelial cell barrier function and rescues retinopathyEMBO molecular medicineJuly 7, 2021Chidiac R, Abedin M, Macleod G, Yang A, Thibeault PE, Blazer LL, Adams JJ, Zhang L, Roehrich H, Jo HN, et al.transferred onto a nitrocellulose membrane and Western blotted using indicated Abs: DVL3 (mAb, Santa Cruz #sc8027, 1:1,000), ZO‐1 (mAb, Invitrogen #339100, 1:1,000), βcatenin (pAb, CST #9587, 1:5,000), β‐Tubulin (mAb,

(12) Nuclear Dishevelled targets gene regulatory regions and promotes tumor growthEMBO reportsJune 4, 2021Castro-Piedras I, Sharma M, Brelsfoard J, Vartak D, Martinez EG, Rivera C, Molehin D, Bright RK, Fokar M, Guindon J, et al.

(13) MEIS-WNT5A axis regulates development of fourth ventricle choroid plexusDevelopment (Cambridge, England)May 15, 2021Kaiser K, Jang A, Kompanikova P, Lun MP, Prochazka J, Machon O, Dani N, Prochazkova M, Laurent B, Gyllborg D, et al.

(14) Canonical and non-canonical Wnt signaling are simultaneously activated by Wnts in colon cancer cellsCellular signallingAugust 1, 2020Flores-Hernández E, Velázquez DM, Castañeda-Patlán MC, Fuentes-García G, Fonseca-Camarillo G, Yamamoto-Furusho JK, Romero-Avila MT, García-Sáinz JA, Robles-Flores M.

(15) Glypican-6 stimulates intestinal elongation by simultaneously regulating Hedgehog and non-canonical Wnt signalingMatrix biology : journal of the International Society for Matrix BiologyJune 1, 2020Shi W, Kaneiwa T, Cydzik M, Gariepy J, Filmus J.

(16) Activity of Smurf2 Ubiquitin Ligase Is Regulated by the Wnt Pathway Protein DishevelledCellsMay 7, 2020Bernatik O, Paclikova P, Sri Ganji R, Bryja V.

(17) NC1-peptide regulates spermatogenesis through changes in cytoskeletal organization mediated by EB1FASEB journal : official publication of the Federation of American Societies for Experimental BiologyFebruary 1, 2020Liu S, Li H, Wu S, Li L, Ge R, Cheng CY.

(18) WNT signaling inducing activity in ascites predicts poor outcome in ovarian cancerTheranosticsJanuary 1, 2020Kotrbová A, Ovesná P, Gybel' T, Radaszkiewicz T, Bednaříková M, Hausnerová J, Jandáková E, Minář L, Crha I, Weinberger V, et al.

(19) Wnt Signaling Pathway Dysregulation in the Aging Brain: Lessons From the Octodon degusFrontiers in cell and developmental biologyJanuary 1, 2020Inestrosa NC, Tapia-Rojas C, Lindsay CB, Zolezzi JM.

(20) Comparative phosphorylation map of Dishevelled 3 links phospho-signatures to biological outputsCell communication and signaling : CCSDecember 23, 2019Hanáková K, Bernatík O, Kravec M, Micka M, Kumar J, Harnoš J, Ovesná P, Paclíková P, Rádsetoulal M, Potěšil D, et al.(Sigma-Aldrich #V 5507), c-Myc (Santa Cruz, #sc-40), α-tubulin (Proteintech, 66,031–1-Ig), anti-DVL3 (sc-8027, Santa Cruz Biotechnology) and anti-β-actin (cs4970, Cell Signalling). Following phospho-specific antibodies

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12/7/2018Dvl3 Antibody that Works, but Not Very Well Mark EHere we were investigating if a novel cytosolic repressor of the Wnt pathway was causing degradation of Dvl2 or Dvl3. Samples with knockdown or overexpression of this repressor were stimulated with ... Read Review

Dvl-3 (4D3) Antibody

Dvl-3 (4D3) Antibody from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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Dvl-3 (4D3) Antibody from Santa Cruz Biotechnology, Inc.

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