Anti-MAP2K2 antibodies are used in the immunodetection of the protein mitogen-activated protein kinase kinase 2. In humans, the canonical protein has a reported length of 400 amino acid residues and a mass of 44.4 kDa. Its subcellular localization is in the membrane and cytoplasm. It is notably widely expressed in many tissue types. A member of the STE Ser/Thr protein kinase protein family, MAP2K2 is known to catalyze the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. Synonyms for this target antigen include MAPKK2, MEK2, MKK2, PRKMK2, dual specificity mitogen-activated protein kinase kinase 2, and CFC4. MAP2K2 gene orthologs have been reported in the mouse, rat, bovine, zebrafish and chicken species. Over 3100 citations in the literature describe the use of MAP2K2 antibodies in research. Western Blot is a widely used application for these antibodies. Immunofluorescence and Immunohistochemistry are also common applications.