What are CXCL16 antibodies?
Anti-CXCL16 antibodies are immunoglobulins that specifically recognize and bind CXCL16, the gene encoding C-X-C motif chemokine 16 in humans. These antibodies are used for immunodetection across general sample types such as tissue samples, cell lysates, and cultured cells. CXCL16 functions both as a scavenger receptor on macrophages that binds oxidized low-density lipoprotein and as a soluble chemokine that induces chemotaxis and calcium mobilization through its receptor CXCR6. Because CXCL16-CXCR6 signaling contributes to atherogenesis, chronic inflammation, and tumor cell invasion, the chemokine is studied across cardiovascular, autoimmune, and oncology research.
Catalog highlights and purchasing considerations
About the Biocompare CXCL16 catalog
The Biocompare antibody search tool lists anti-CXCL16 antibodies from a range of suppliers, spanning polyclonal and monoclonal formats validated across multiple applications. Listings may also appear under alternate names such as SR-PSOX and CXCLG16. Western blot, flow cytometry, and ELISA are the most common validated applications among these products. In addition, the CXCL16 antibodies mentioned here have been cited across a range of inflammation and cancer research, including studies on IL-23-driven immune cell migration in renal fibrosis, lung and ovarian cancer progression, and rheumatoid arthritis-associated angiogenesis.
Considerations when choosing a CXCL16 antibody for research
Confirm that the antibody's intended target is accurate, as many genes carry synonym symbols that can create ambiguity across suppliers. Specificity should be verified against the immunogen sequence or region listed on the product datasheet, since antibodies raised against different epitopes of the same protein can behave differently across applications. Beyond specificity, several target-related attributes can affect antibody binding, including subcellular location, extracellular and cytoplasmic domain boundaries for membrane-associated targets, tissue specificity, post-translational modifications, and the presence of additional isoforms or disease-associated variants. In parallel, antibody-specific selection criteria include clonality (monoclonal versus polyclonal), host species, species reactivity, and the choice of conjugate or label suited to the intended detection method. Supplier-provided validation data, such as western blot bands at the expected molecular weight, immunohistochemistry staining patterns consistent with known tissue distribution, or knockout and knockdown controls, is widely regarded as the most reliable final check before purchase.