Anti-5-HT3c1 antibodies enable researchers to detect and measure the 5-HT3c1 antigen in biological samples. This target is a reported synonym of the HTR3E gene, which encodes 5-hydroxytryptamine receptor 3E. This protein is known to function in chemical synaptic transmission and signal transduction pathways, among other biological roles. The human version of 5-HT3c1 has a canonical amino acid length of 456 residues and a protein mass of 51.4 kilodaltons, although 5 isoforms have been identified. It is reported to be localized in the cell membrane of cells and notably expressed in the spleen, small intestine, duodenum, bone marrow, and appendix. 5-HT3c1 is a member of the Ligand-gated ion channel (TC 1.A.9) protein family.