Excellent Nuclear-Fraction Marker

Biochemistry
Stanford University
Postdoctoral Researcher

Overall

Quality of Results

Ease-of-Optimization

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Company:

Proteintech

Product Name:

Lamin A/C Polyclonal antibody

Catalog Number:

10298-1-AP

Clone Number:

I frequently separate nuclear and cytoplasmic compartments to track where signaling proteins and transcription factors localize. I use this Lamin A/C antibody as a nuclear loading/fractionation marker by western blot to confirm clean subcellular separation.

Experimental Design and Results Summary

Applications

Western Blot

Sample

Cell lysate

Primary Incubation

1:5000

Blocking Agent

5% milk in TBST

Secondary Incubation

None

Tertiary Incubation

None

Detection

Chemiluminescence

Results Summary

Detected Lamin A/C as two clean, specific bands confined exclusively to the nuclear and total fractions with no cytoplasmic signal, confirming proper fractionation.

Image Gallery

Summary

The Good

Exceptionally specific and sensitive

The Bad

None

The Bottom Line

A gold-standard nuclear marker antibody for fractionation

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