Editorial Articles

Comprehensive overviews of enabling tools and techniques, as well as trends, researched and written by Biocompare writers.

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Key Considerations for SYBR Green Real-Time PCR
August 28, 2012
SYBR® Green is a dye that intercalates into DNA and has many applications in molecular biology. One such application is real-time PCR, also known as ... read more
Transcriptome Analysis Using RNA-Seq
September 04, 2012
Today, transcriptome analysis is performed most commonly using an NGS application called RNA-seq, in which an RNA pool is reverse-transcribed into ... read more
Tools for Efficient Next Gen Sequencing Sample Prep
September 11, 2012
Next generation sequencing sample preparation tools are available from both sequencer manufacturers and third-party vendors. These reagent kits ... read more
Research Tools for Three-Dimensional Cell Culture
September 18, 2012
In three-dimensional (3D) cell culture, cells are grown in environs constructed to better resemble their original in vivo homes. Increasing evidence ... read more
Cell Proliferation Assays: Methods for Measuring Dividing Cells
September 25, 2012
In a cell proliferation assay, you measure the number of cells, or the change in the proportion of cells, that is dividing. There are four main types ... read more
Lab Apps for Scientists
October 02, 2012
Smartphones and tablets have entered the lab environment, and for most routine lab tasks, there probably really is an app for that. Check out the ... read more
Lentiviral Expression – A High Titer Toolbox
October 09, 2012
Lentiviruses are excellent molecular tools for expressing (or silencing) a gene of interest through infection of target cells, either in vitro or in ... read more
Overcoming the Challenges of Multiplex PCR
October 23, 2012
When designing a working polymerase chain reaction, primer design, reaction conditions, and enzyme selection must all be considered. This complexity ... read more
Peptide Synthesis: What Level of Purity Do You Need?
October 25, 2012
Most peptide synthesis services purify products using reverse-phase high-performance liquid chromatography (HPLC), though sometimes alternative ... read more
What to Look for in an Electroporator
October 30, 2012
Electroporation is a tailored combination of buffer conditions and electrical pulses that opens transient pores in the cell membrane, allowing nucleic... read more
Maximize Your NGS with Sequence Capture
November 06, 2012
Sequence-capture technologies, as their name suggests, allow users to specifically pull out a desired fraction of a sample for sequencing, thereby ... read more
Top 4 Features to Look For in an ELISA Kit
November 13, 2012
Most ELISA kits are designed to determine the concentration of an antigen in an unknown sample, and they are faster and more convenient (possibly also... read more
In Vitro Tools Offer Flexibility for Large Scale Monoclonal Antibody Production
November 15, 2012
Monoclonal antibodies (mAbs) are essential tools for research scientists in a range of biological and biochemical disciplines. As molecules designed ... read more
Get the Blight Out: 5 Common Methods of Mycoplasma Detection
November 20, 2012
Mycoplasma refers to any of over 200 species of tiny (0.2-0.8 µm diameter) bacteria that commonly invade cell cultures, and may even persist ... read more
Five Important Features of a Standard Thermal Cycler
November 26, 2012
Thermal cyclers, also known as thermocyclers or PCR machines, are important basic instruments relied upon in nearly all molecular biology labs and ... read more
The Disease Fighting Potential of Long Non-coding RNAs
November 29, 2012
Long noncoding RNAs (lncRNAs) are mysterious molecules. They are almost-proteins—transcripts of about 200 or more nucleotides that appear not to ... read more