Editorial Articles

Comprehensive overviews of enabling tools and techniques, as well as trends, researched and written by Biocompare writers.

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Gene Expression Analysis Tools for Non-Model Organisms
February 27, 2014
Using next-generation DNA sequencing, cloud computing and in silico design tools, anyone can become expert in the gene expression of organisms outside... read more
Never Miss a Variant Again with These Sequence-based CNV Detection Tools
February 25, 2014
Though they traditionally used microarrays or FISH, researchers increasingly are turning to NGS to extract CNV information. There are dozens of ... read more
Motion Tracking in Live-Cell Imaging
February 20, 2014
An important facet of live-cell imaging is motion tracking—using microscopes and software to follow the position of cells or subcellular structures as... read more
No NGS, No Problem. Outsource Your Analyses with These MicroRNA Service Providers
February 18, 2014
For many researchers, microRNA discovery and investigation are more a means to an end than the focus of their research. Or perhaps they simply are ... read more
Next-Gen Sequencing 2014 Update
February 13, 2014
It’s been a busy year in the world of next-gen sequencing. Here, just in time for this year’s annual Advances in Genome Biology and Technology (AGBT) ... read more
Count Your Nucleic Acids with These Digital PCR Systems
February 11, 2014
Digital PCR (dPCR) is largely seen as the next step in the evolution of PCR—it enables reliable, absolute quantification of rare alleles in minute ... read more
Never Fail to Deliver with these Stem Cell Transfection Tools
February 06, 2014
Stem cells, provide several unique transfection challenges. Pluripotent stem cells, for instance, often are grown in colonies, leading to cell ... read more
These 2D Gel Tools Will Have You Seeing (Well-Resolved) Spots
January 30, 2014
2D gel electrophoresis can individuate thousands of proteins on a single gel. Researchers typically use it to compare expression levels in different ... read more
The Secrets of ChIP Success: Three Tips for Better Chromatin IP
January 28, 2014
In theory, ChIP, RIP and MeDIP are simple. In practice, they are anything but. Here we review three key variables to bear in mind as you set about ... read more
Get the Big Picture with Top-Down Proteomics
January 23, 2014
Proteomics can be bottom-up or top-down. The former is easier, the latter, more comprehensive -- especially when it comes to distinguishing one "... read more
These Luminometers Will Give You Data in a Flash (of Light)
January 21, 2014
Luminometry is helping to answer ever more pressing questions in the biological laboratory. It requires neither special expertise nor particularly ... read more
Your Cells Can Breathe Easy in these Nonstandard Culture Environments
January 16, 2014
Since at least the 1960s, researchers have reported differential effects of culturing cells in reduced oxygen (hypoxia), and many researchers now ... read more
Study Your Cells sans Fluorophores with these Label-Free Analysis Systems
January 14, 2014
Cell biology with neither labels nor molecular tags may puzzle researchers learned in fluorophores and fluorescent proteins, but that doesn't mean you... read more
Scan Your Slides and Share Your Data with these Digital Pathology Systems
January 09, 2014
Digital pathology systems enable the automated scanning, imaging and storage of histological slide data for analysis by pathologists. Less vulnerable ... read more
Free Up Your Freezer with These Room-Temperature DNA Storage Solutions
January 07, 2014
It’s a maxim as old as molecular biology itself: You don’t store DNA on the bench. DNA typically is stored frozen, requiring significant capital and ... read more
Ditch Your Agarose with These Automated Electrophoresis Tools
January 02, 2014
Let’s face it, gel electrophoresis is a pain. Pre-cast gels and pre-made buffers make things a little easier, but many researchers would still welcome... read more