Editorial Articles

Comprehensive overviews of enabling tools and techniques, as well as trends, researched and written by Biocompare writers.

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Chromosomes Customized While-U-Wait with Genome-Editing Services
January 27, 2015
With each new technical advance, genome editing becomes ever more accessible. Yet it’s still not a trivial matter to create a homogenous cell line ... read more
Average, Shmaverage! Embrace Heterogenity with Single-Cell Transcriptomics
January 23, 2015
Researchers have over the past few years developed tools to downsize their research to the single-cell level. Some are based on next-generation DNA ... read more
Fluorescence or Chemiluminescence: Which Reporter Is Right For You?
January 21, 2015
Reporters generally come in two flavors, fluorescent or luminescent. Oftentimes, expression plasmids are available with either type of reporter, and ... read more
Detecting Circulating Tumor Cells
January 19, 2015
Oncologists traditionally rely on invasive biopsies and non-invasive imaging modalities to track tumor size and spread. Circulating tumor cells (CTCs)... read more
Clean Your Cultures with These Mycoplasma-Elimination Tools
January 13, 2015
Given the widespread yet unpredictable effects of mycoplasma on cells in culture, researchers have every reason to avoid contamination. But what ... read more
Testing for Food Contamination
December 30, 2014
Whether prepared in a restaurant or sold in grocery stores, consumers want to know their food is safe. That’s the job of food-testing laboratories, ... read more
Keep Your Rotors Spinning with These Centrifuge Cleaning and Maintenance Tips
December 26, 2014
You know you should probably clean your centrifuges regularly, but do you know exactly how to do it, and when? Do you know how to perform other ... read more
Automating Immunohistochemistry
December 24, 2014
There are about a dozen automated IHC staining systems on the market. Although it may not be easy to tell apart the slides that ultimately emerge from... read more
See Neurons Clearly with CLARITY
December 16, 2014
Researchers have devised strategies to make brains optically transparent, thereby obviating the need for thin tissue sectioning. One, published in ... read more
Cell Lines for Ion-Channel Screening
December 02, 2014
Testing drugs on ion channels is complicated by multiple factors, including the fact that neurons contain numerous channels capable of responding to ... read more
Neuronal Cell Culture: You've Got Some Nerve
November 19, 2014
Between arduous isolation procedures and finicky culture conditions, neurons have the reputation of being some of the most challenging cells to grow. ... read more
Bioinformatics Tools for lncRNA Research
November 14, 2014
Researchers increasing recognize the functional importance of long noncoding RNAs, and for the most part, the tools to study them already are in place... read more
Next-Gen DNA Sequencing: Fall 2014 Update
November 12, 2014
Sequencing instrumentation hasn’t changed since we looked at the market in February 2014, but that’s not to say all is as it was. New sample-... read more
FFPE or Frozen? Working with Human Clinical Samples
November 07, 2014
Peering into human tissues—to study morphology, cell biology, biochemistry and more—is made possible using sections of biopsied tissue that have been ... read more
Nature's Vectors: Picking the Right Viral Expression System
November 04, 2014
Viruses have evolved along with just about every species studied, and they have developed crafty ways of insinuating themselves into cells and turning... read more
Picking the Perfect HPLC Column
October 31, 2014
High-pressure liquid chromatography (HPLC) is one of the most popular methods for separating molecules in a heterogeneous sample. The key, of course, ... read more