Limited Performance Observed with Rabbit Polyclonal Unc93a Antibody

Health Division of Gastroenterology
UC Davis

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Company:

Abcam

Product Name:

Rabbit Polyclonal Unc93a antibody

Catalog Number:

ab69443

Clone Number:

N/A

We created a construct for the overexpression of UNC93A and transiently transfected it into HEK293T cells. The FLAG-tagged UNC93A protein was easily detected with an anti-FLAG antibody. However, we were unable to identify a corresponding band using the UNC93A antibody, even at a dilution of 1:100. These results indicate that while the overexpression construct is successfully expressed, the antibody does not recognize UNC93A under the conditions used for Western blotting.

Experimental Design and Results Summary

Applications

Western blot

Sample

HEK293T cells

Primary Incubation

1:100 dilution, overnight

Blocking Agent

3% BSA in PBS

Secondary Incubation

1:1000 goat anti-rabbit

Tertiary Incubation

1hr incubation at room temp

Detection

LICOR fluorescence

Results Summary

We generated an UNC93A overexpression construct and transiently transfected it into HEK293T cells. While the FLAG-tagged UNC93A protein was readily detected using an anti-FLAG antibody, we were unable to detect a corresponding band using the tested UNC93A antibody. These results suggest that the overexpression construct is expressed successfully, but the antibody does not recognize UNC93A under Western blot conditions even at a 1:100 dilution.

DOI or PMID #

N/A

Additional Notes

N/A

Related Categories

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Summary

The Good

None.

The Bad

Not working.

The Bottom Line

This antibody doesn't work for recognizing UNC93A protein.

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