Reliable Kit From ThermoFisher for Bacterial Live-Dead Cell Staining

The Scripps Research Institute
Immunology Microbiology
Postdoctoral Researcher

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Company:

Thermo Fisher Scientific

Product Name:

LIVE/DEAD™ BacLight™ Bacterial Viability Kit, for microscopy & quantitative assays

Catalog Number:

L7012

Info: Supplier Page 

I made a cell wall hydrolase knockout in E. coli and I observed decreased growth in a growth curve. To investigate whether the effect is bacteriostatic or bactericidal, I have used this kit to figure out live and dead cells.

Experimental Design and Results Summary

Application

To examine the viability of bacteria.

Starting Material

N/A

Tips

Wash your cells thoroughly to decrease the background stain.

Results Summary

I have imaged a cell wall hydrolase mutant bacteria after staining them with the mixture of dyes containing Syto9 and Propidium Iodide (PI) from the kit and observed red-colored cells indicating that the mutant cells are lysing.

DOI or PMID #

30940749

Image Gallery

Summary

The Good

Convenient and easy-to-use kit.

The Bad

Expensive.

The Bottom Line

This kit is useful to quickly examine the viability of cells.

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