MTT Assay for Cell Viability

Stanford University
Department of Pathology
Postdoctoral Researcher

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Company:

MilliporeSigma

Product Name:

Thiazolyl Blue Tetrazolium Bromide (MTT)

Catalog Number:

M5655

I used the MTT assay as a simple, rapid, and reliable indicator of the cell viability of cultured cells under different treatment conditions.

Experimental Design and Results Summary

Application

Cell viability

Starting Material

Cultured cells

Tips

Use negative and positive controls.

Results Summary

Cells were plated in 96-well culture plate. After treatment, MTT solution (0.5 mg/ml in growth medium) was added followed by incubation for further 3 h under normal growth conditions. Medium was removed and formazan crystals were dissolved in DMSO. Absorbance was measured at 570 nm using a plate reader.

DOI or PMID #

https://doi.org/10.1016/j.jmb.2019.01.022

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Summary

The Good

Ease of use, and rapid.

The Bad

None.

The Bottom Line

Easy assay to measure cell viability.

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