MilliporeSigma
P-SMAD2
AB3849-1
N/A
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Browse Similar Products: SMAD2 Antibodies
Smad proteins SMAD2 and SMAD3 are core transcription factors involved in TGF-beta signaling, and they interact with cofactors to control the expression of TGF-beta-dependent genes. The principal receptor-activated Smads involved in signaling from TGF-β receptors are Smad2 and Smad3. In the nucleus, Smad proteins can bind directly to their cognate DNA-binding sites and/or interact with an increasing number of transcription factors, transcriptional coactivators, or transcriptional repressors.
Western Blot
Mouse tissue liver and Heart
1:250 dilution overnight incubation
1% BSA prepared in 1X TBST
1:250 dilution 1% BSA prepared in 1X TBST for 2hrs
None
Fluorescent microscope
Smad2 and Smad3 are similarly proposed to act downstream of TGFβ signaling. in our results we found mouse tissue heart samples increased p-SMAD2 levels.
NA
Great
Highly recommended to this immunostaing.