BD Biosciences
BD Horizon™ BUV737 Mouse Anti-Human CD138
564393
MI15
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Antibodies are produced by plasma cells (PC) that are terminally differentiated B cells and play crucial roles in host protection against infections but are considered to mediate autoimmunity in patients with rheumatic diseases, such as systemic lupus (SLE) or rheumatoid arthritis (RA). Our research aims at understanding the biology of B cells and antibody-secreting cells (ASC) in health and disease, in this experiment, we are looking for markers of PC, so we stain them using anti-CD138.
Flow Cytometry
Human BM
Surface staining with CD138 BUV737, 20 min at 4C
Fc block
N/A
Flow cytometry
In this work, we were looking for surface markers that are differentially expressed by B cells (CD19+) and plasma cells (PC). We stained BMPC using CD138 and CD38, two well established markers of PCs.
35464469
Good signal.
It is expensive.
Antibody has great signal!