Bright C3/C3b/iC3b Staining on Platelets

Hem/Onc
Boston Children's Hospital
Postdoctoral Researcher

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Company:

BD Biosciences

Product Name:

BV750 Mouse Anti-C3/C3b/iC3b

Catalog Number:

752717

Clone Number:

6C9

Info:Supplier Page View Product Specs

Browse Similar Products: iC3b Antibodies

BV750 Mouse Anti-C3/C3b/iC3b recognizes the components and fragments of complement C3, which may be present on the platelet surface in certain pathologic states. Bright C3b staining on human platelets.

Experimental Design and Results Summary

Applications

Flow Cytometry

Sample

Human whole blood collected in sodium citrate

Primary Incubation

30 min at room temperature

Blocking Agent

Staining buffer contains 0.5% BSA

Secondary Incubation

N/A

Tertiary Incubation

N/A

Detection

Fluorescence

Results Summary

Citrate-anticoagulated human whole blood was diluted 1:10 in HEPES-Tyrodes-BSA containing BV750 Mouse Anti-C3/C3b/iC3b with or without 10 µg/mL Anti-GPIIb/IIIa [10E5] (complement activator). 10E5-treated platelets show bright staining for complement C3.

DOI or PMID #

N/A

Additional Notes

N/A

Image Gallery

Summary

The Good

Bright C3b staining on human platelets.

The Bad

N/A

The Bottom Line

BV750 Mouse Anti-C3/C3b/iC3b allows bright staining of complement components and fragments on the surface of human platelets.

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