Affordable Monocyte Marker

Chemical/Biomedical Engineering
University of Toronto
PhD Candidate

Overall

Quality of Results

Ease-of-Optimization

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Company:

BD

Product Name:

Ly6g BUV563

Catalog Number:

612921

Clone Number:

1A8

Info:Supplier Page View Product Specs

Browse Similar Products: Ly6g Antibodies

We are interested in using cutting edge single cell analysis methods (spectral flow cytometry, scRNAseq, etc) to study the mechanisms responsible for establishing and maintaining immune tolerance.

Experimental Design and Results Summary

Applications

Flow Cytometry

Sample

Mouse Lymph nodes, spleen

Primary Incubation

Block: 1:50 in 100uL at 37C for 30 min

Blocking Agent

Fc Block (aCD16/32)

Secondary Incubation

L/D: Zombie NIR 1:4000 in 100 uL at RT for 20 min

Tertiary Incubation

Surface stain: 1:500 in 100uL at 4C for 30 min

Detection

Spectral flow cytometry (Cytek Aurora)

Results Summary

This antibody weakly stains monocytes well enough to identify Ly6G+ cells, but not well enough to get a high dynamic range of expression. Ok for general immune cell population studies, but not for targeted study of Ly6G.

DOI or PMID #

N/A

Additional Notes

N/A

Image Gallery

Summary

The Good

Cheap, acceptable staining

The Bad

Somewhat mediocre signal strength.

The Bottom Line

An ok monocyte antibody.

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