CD57 with Good Separation

Pathology
UMass
Lab Technician

Overall

Quality of Results

Ease-of-Optimization

What do these ratings mean?
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Company:

Beckman Coulter

Product Name:

CD57-FITC, NC1, 2 mL, ASR

Catalog Number:

IM0466U

Clone Number:

NC1

Info:Supplier Page View Product Specs

Browse Similar Products: CD57 Antibodies

We selected this antibody to test for CD57 on NK cells, which is useful in the follow-up of patients with Lyme disease.

Experimental Design and Results Summary

Applications

Flow Cytometry

Sample

PBMC (NK cells)

Primary Incubation

10 minutes at room remp

Blocking Agent

1% FBS

Secondary Incubation

N/A

Tertiary Incubation

N/A

Detection

FL-1 channel (on almost all cytometers)

Results Summary

The results we got are encouraging. We can often see a good separation between negative and positive NK cells. Sometimes, the boundary is hazy but this may reflect the biology. Also, FITC is a dim fluorochrome, so maybe a brighter fluor will yield better separation.

DOI or PMID #

N/A

Additional Notes

N/A

Image Gallery

Summary

The Good

Good separation. Reasonable price. ASR.

The Bad

Need to use 20uL per test.

The Bottom Line

This is a good antibody, available at a reasonable price, and works without the need for extensive optimization.

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