Efficient CD3 Antibody

Pathology
UMass
Lab Technician

Overall

Quality of Results

Ease-of-Optimization

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Company:

Beckman Coulter

Product Name:

CD3-PC5, UCHT1, 1 mL, ASR

Catalog Number:

IM2635U

Clone Number:

UCHT1

Info:Supplier Page View Product Specs

Browse Similar Products: CD3 Antibodies

CD3, a typical T cell marker, is available in all colors and from all vendors! However, finding a good CD3 antibody is not always straightforward. Here, I show that this antibody is a winner, and it's easy to use and optimize.

Experimental Design and Results Summary

Applications

Flow Cytometry

Sample

Human blood cells

Primary Incubation

10 minutes at Room Temperature

Blocking Agent

1% fetal calf serum

Secondary Incubation

N/A

Tertiary Incubation

N/A

Detection

Flow cytometer: 695/30 filter

Results Summary

The results show a very well-defined peak of CD3 positive T cells (green) in the lymphocyte (L) population (red). There is very good separation of the positive cells from the negatives. The mean fluorescence intensity is excellent, and this will give you a very good stain index (SI). It's really easy to optimize - 2-5uL of the antibody is good enough.

DOI or PMID #

Additional Notes

Related Categories

Image Gallery

Summary

The Good

Easy to use. Strong signal. Good negative.

The Bad

A little bit expensive.

The Bottom Line

For an easy to use CD3 antibody, read on the blue laser (Emission spectrum around 600nm), this antibody does the job.

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