Gives Good Results for Protein Clean Up

Children's National Research Institute
Genetics Medicine
Graduate Student

Overall

Quality of Results

Ease-of-Optimization

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Company:

Invitrogen

Product Name:

Dynabeads™ Protein G Immunoprecipitation Kit

Catalog Number:

10007D

Info: Supplier Page 

I am studying a protein that is usually responsible for male gonad differentiation in mammals but is recently found out to be implicated in Parkinson's disease (PD). This protein is not present in the flies and I am trying to express it in the brain of the animal to check if its expression would cause changes/phenotypes that can be linked to PD.

Experimental Design and Results Summary

Application

Check presence of absence of protein in Western Blot

Starting Material

Protein

Tips

Have additional wash (from 3, increase it to 5) after the Ab-Ag binding to ensure cleaner results

Results Summary

SRY protein (the protein I was trying to express in Drosophila) was clearly detected in Western Blot.

DOI or PMID #

N/A

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Summary

The Good

Fast and intuitive

The Bad

Need extra washing steps to clean up protein of interest

The Bottom Line

The kit is quite expensive but it would save you time for your experiments.

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