Detection of Total ROS Level in Primary Microglia

Medical University of Graz
Molecular Biology and Biochemistry
Postdoctoral Researcher

Overall

Quality of Results

Ease-of-Optimization

What do these ratings mean?
Write a Review

Company:

Enzo

Product Name:

ROS-ID® Total ROS detection kit

Catalog Number:

ENZ-51011

Primary murine microglia cells were treated with LPA in the presence or absence of different MAPK inhibitors and the total ROS levels were detected after different time periods.

Experimental Design and Results Summary

Application

Total ROS assay

Starting Material

Primary murine microglia

Tips

Perform multiple experiments, there is increased variation between replicates.

Results Summary

Inhibition of MAPK signalling decreased the LPA induced production of ROS.

DOI or PMID #

https://doi.org/10.1186/s12974-020-01809-1

Image Gallery

Summary

The Good

Easy and fast to use.

The Bad

High variation between replicates. The reconstituted detection reagent has a shelf life of just 1 week.

The Bottom Line

An easy to use kit as long as you optimize it.

Join the discussion