Great Histone H3 (D1H2) for Western Blot

Medicine
Harvard Medical School
Post-doctoral fellow

Overall

Quality of Results

Ease-of-Optimization

What do these ratings mean?
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Company:

Cell Signaling Technologies

Product Name:

Histone H3 (D1H2) XP® Rabbit mAb (HRP Conjugate)

Catalog Number:

12648S

Clone Number:

N/A

I used this antibody as a loading control for nuclear fraction of THP1 cell samples treated with different compounds.

Experimental Design and Results Summary

Applications

Western Blot

Sample

THP-1 cells treated with different compounds

Primary Incubation

1:1000 dilution, 18 hours at 4 degrees with gentle shaking

Blocking Agent

5% non-fat dry milk in Tris buffer containing 0.1% Tween-20

Secondary Incubation

None

Tertiary Incubation

Not applicable

Detection

ECL based detection

Results Summary

This antibody is a great nuclear marker. If you are extracting nuclear fraction to study nuclear proteins, I highly recommend using this as a loading control.

DOI or PMID #

N/A

Additional Notes

N/A

Related Categories

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Summary

The Good

High sensitivity

The Bad

Nothing

The Bottom Line

This antibody works great for Western blotting purposes.

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